Benefits of L-Carnosine for Autistic Children

Possible Benefits of L-Carnosine for Children with Autism - Benefits of L-Carnosine for Autistic Children. L-Carnosine is an amino acid that occurs naturally in the body. The highest concentrations of L-Carnosine are found in the heart, muscle, and brain tissues. Carnosine is classified as a dipeptide, which is a compound made up of amino acid molecules that are linked together. It is thought to enhance frontal lobe function in the brain, and research suggests that it is also a powerful antioxidant.

A synthetic form of carnosine is available, and sold as a supplement to help treat a variety of health issues. These include liver disease, cancer, cataracts, and Alzheimers disease. It is also marketed as an anti-aging nutrient. Some doctors and researchers also claim that carnosine can be of tremendous help to children with autism.

Research indicates that carnosine may help autistic children in a variety of ways, mainly centering around the child’s behavior, and language skills, and it may enhance nervous system function. Studies have reported that children who take carnosine supplements have shown improvement in the following areas:

  • vocabulary
  • language comprehension
  • communication
  • socialization
  • object recognition
  • awareness of surroundings
  • fine motor skills
  • auditory processing

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A double blind, placebo controlled study of carnosine was conducted by Doctor Michael G. Chez, and several other researchers. In the study, thirty one autistic children between the ages of three to twelve years were treated with either a carnosine supplement, or a placebo. The study lasted eight weeks, and by the end most of the children who had been taking the carnosine supplements showed significant improvement in behavior, socialization, and communication skills. The amount and percentage of the childrens improvement was based on the standards of the Childhood Autism Rating Scale (CARS), the Gilliam Autism Rating Scale (GARS), and the Expressive and Receptive One-Word Picture Vocabulary tests (E/ROWPVT). Reports given by the childrens parents were also used in the assessment of the childrens overall improvement. The children who had been taking the placebo instead of the carnosine, showed no improvements. The researchers stated that, “Oral supplementation with L-Carnosine resulted in demonstrable improvements in autistic behaviors, as well as increases in language comprehension that reached statistical significance.”

The results of the study were published in the Journal of Child Neurology in 2002. The original article and more details about Doctor Chezs study can be found here:

Research indicates that the benefits of carnosine supplementation in autistic children are usually seen within one to eight weeks after the child begins taking it. Carnosine is tolerated very well by diabetics, and is compatible with both ketogenic, and gluten/casein free diets. It has also been reported that it may improve some EEG abnormalities and the frequency of both myoclonic and generalized seizures.

To date, there have been no harmful physical side effects reported by those taking carnosine. However, too high a dose may overstimulate some children, causing hyperactivity, irritability, or insomnia. This mainly occurs in children that have already been diagnosed as being manic or hyperactive, and the side effects usually resolve if the dose of carnosine is adjusted. Many parents have reported that their children seem to sleep better once they are on carnosine as well.

Although research indicates that carnosine may be a very beneficial supplement for children with autism, it is important to note that the studies that have been conducted are relatively recent, and there is much about carnosine that may still be unknown. A physician should always be consulted before starting any natural or over the counter supplement.


This article was featured in Issue 17 – Autism Awareness and Acceptance!


Megan Kelly

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Patty - February 29, 2016 Reply

What dose of carnosiine would we give a 8 year old male?

    Simon - May 5, 2016 Reply

    Hi we tried 400ml with our 4 year old. There were no negative side affects and some positive results. Hard to tell what was down to the medication or general progress at that age though

      Simon - May 5, 2016 Reply

      It was actually 400mg twice a day which was about three quarters of a capsule twice a day

        Lizzy - July 12, 2016 Reply

        My non Verbal four year old has started to talk. I give 200mg twice a day, as the larger doses stopped her from sleeping. She is repeating everything I say and her comphrension and cognitive functions have improved. My daughter has stopped skimming and spinning. I have lots of spontaneous speech and genuine requesting. I am very happy that Dr Chez did this triail. This treatment is safe and does not cause other problems. Thanks Dr Chez, Lizzy, Australia

          Hameem - September 14, 2016 Reply

          We tried this on my 2.5 year old and he shows good improvement. However, after 8 week we reduced the quantity by half and we started to see hyper active behavior again. I have couple of questions. Are there any recommendation on how long this supplement to be used ? Can this be used along with early intervention programs ?

Tash - February 17, 2017 Reply

Hi, can anyone tell me of a note worthy carnosine supplier. I live in Australia. But need to import because not avail here.

    Rachel - February 23, 2017 Reply

    My son’s doctor had us order the L-carnosine online from Kirkman Labs. He trusted their quality. Also, they sell it in 200mg capsules, which works better for dosaging. Good luck!

Ananth - September 30, 2017 Reply


Can anyone in India suggest where we can get this tablet and What is the dosage to be given

    Arleen - October 8, 2017 Reply

    Hello Ananth, ships internationally and they do ship to India. They sell their own brand and name brands supplements. They sell this supplement in capsule and tablet.

    The brand called NOW, is of good quality, which is the one I use. You can research the brands and check the ingridients before you purchase.

    Hope this helps.

      Ananth - October 28, 2017 Reply

      Thanks Arleen for your response. My son is 7 yrs and could you please advise the dosage if I go with tablet and also the duration of the dosage.

      Thanks again

        Ananth - November 2, 2017 Reply

        Hi Ananth,

        You can get this in syrup. You can buy in India.

        Hope this helps.

          Sankar - November 10, 2017 Reply

          you can get in India in anyware in major cities/Towns

    Sini - March 16, 2018 Reply

    L carnosine liquid is available in certain pharmacies in India but you need prescription.

    Aravin - July 31, 2018 Reply

    You can get from brio bliss distributor. They having it in Syrup form under they branding cognicare.

Judy - November 21, 2017 Reply

what dose would you suggest for a 10yr

    zeinab elmi - January 23, 2018 Reply

    in the research they used 400 mg twice a day. I have a 13 years old that I just started with. I give him 400 once a day and then will increase it to twice in a weeks time.

      Melanie - March 10, 2018 Reply

      What is the weight of your 13 year old? I have an 11 yhear old but she only weighs 60 pounds (on a good day) so I am afraid that may be too much for her

Tracy - November 21, 2017 Reply

Is this beneficial for adults with autism ?

Susana Henry - May 4, 2018 Reply

Hi my son is autism speaking in one word and hyperactive..shal I buy this..will it affect any other parts..give me suggestions or it is drowsy medicine..Pls explain

Arpitha - September 10, 2018 Reply

How long have uu been using it? I read there will b regression once u stop using it

Vihang - September 15, 2018 Reply

3.5 year old child diagnosis mild Autism Dr suggest brainwise Syrup & cognicare Syrup for BD it’s useful for child please tell me this medicine no side effects sure

apeksha - December 3, 2018 Reply

Hi, my son is 2.5 yrs old and dr diagnosis mild autism…He give us brain wise and ten on ten and congnicare ….Could u plz suggest should I give him L carnosine liquid or syrup ??? And where can I get this medicine? And also suggest how much qty should I give liquid or capsule?? Plzz suggest asap

    Edna - December 3, 2018 Reply

    Hi Apeksha! Thanks so much for reaching out to us – your question is an interesting one. We suggest you talk to your child’s pediatrician or family doctor about your concerns on whether to give your child the syrup type of L-Carnosine as well as how many or how often should you give him. Be sure to tell the doctor all your questions and have them noted. Hope your next appointment goes well and you get the answers you need.

mohammad - January 5, 2019 Reply

Hi Dear Friends
I need help. my daughter is 2.5 yrs old and dr diagnosis of mild autism. But my daughter was more talkative from 18 months to 26months. But suddenly she stops talking more in 27 months. She was using more youtube those days and addicted to youtube. so she was just singing rhymes of youtube and other words our mother tongue she was not using. so please suggest what to do where shall I go to which doctor. I’m living in Hyderabad. please help me.

    Edna - January 13, 2019 Reply

    Hi Mohammad! Thanks so much for reaching out to us. We suggest you talk to your child’s pediatrician or family doctor about your concerns and to get the right solutions for your child’s situation. Be sure to tell the doctor all your concerns. Hope your next appointment goes well and you get the answers you need.

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